Clinical significance: Difference between revisions
Editor iHTS (talk | contribs) (Created page with "A difference in effect size that the experts consider significant for clinical or strategic decisions, regardless of statistical significance. '''Note:''' In a trial with a large number of subjects, a small difference between the treatment group and the control group may be statistically significant, but clinically unimportant. In a trial with a small number of subjects, an important clinical difference may be observed that is not statistically significant. A larger tri...") |
No edit summary |
||
| Line 3: | Line 3: | ||
'''Note:''' In a trial with a large number of subjects, a small difference between the treatment group and the control group may be statistically significant, but clinically unimportant. In a trial with a small number of subjects, an important clinical difference may be observed that is not statistically significant. A larger trial may be needed to confirm that the difference is statistically significant. | '''Note:''' In a trial with a large number of subjects, a small difference between the treatment group and the control group may be statistically significant, but clinically unimportant. In a trial with a small number of subjects, an important clinical difference may be observed that is not statistically significant. A larger trial may be needed to confirm that the difference is statistically significant. | ||
== Reference == | |||
http://htaglossary.net/clinical-signifiance | |||
Latest revision as of 12:09, 9 November 2023
A difference in effect size that the experts consider significant for clinical or strategic decisions, regardless of statistical significance.
Note: In a trial with a large number of subjects, a small difference between the treatment group and the control group may be statistically significant, but clinically unimportant. In a trial with a small number of subjects, an important clinical difference may be observed that is not statistically significant. A larger trial may be needed to confirm that the difference is statistically significant.