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	<title>Factorial design - Revision history</title>
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	<updated>2026-10-17T04:37:09Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>http://glossary.i-hts.org/index.php?title=Factorial_design&amp;diff=790&amp;oldid=prev</id>
		<title>Admin1 at 13:08, 21 November 2023</title>
		<link rel="alternate" type="text/html" href="http://glossary.i-hts.org/index.php?title=Factorial_design&amp;diff=790&amp;oldid=prev"/>
		<updated>2023-11-21T13:08:51Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:08, 21 November 2023&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l3&quot;&gt;Line 3:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 3:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Note:&amp;#039;&amp;#039;&amp;#039; Most trials consider only one experimental intervention, comparing it with one or more options or a placebo. In a trial using a 2x2 factorial design, participants are allocated to one of four possible combinations.  For example, in a randomised controlled trial of a nicotine replacement therapy and counselling, participants would be allocated to: nicotine replacement therapy alone, counselling alone, both, or neither. In this way it is possible to test the independent effect of each intervention on smoking cessation and the combined effect of (interaction between) the two interventions.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Note:&amp;#039;&amp;#039;&amp;#039; Most trials consider only one experimental intervention, comparing it with one or more options or a placebo. In a trial using a 2x2 factorial design, participants are allocated to one of four possible combinations.  For example, in a randomised controlled trial of a nicotine replacement therapy and counselling, participants would be allocated to: nicotine replacement therapy alone, counselling alone, both, or neither. In this way it is possible to test the independent effect of each intervention on smoking cessation and the combined effect of (interaction between) the two interventions.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[&lt;/del&gt;http://htaglossary.net/factorial-design&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Reference ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;http://htaglossary.net/factorial-design&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Admin1</name></author>
	</entry>
	<entry>
		<id>http://glossary.i-hts.org/index.php?title=Factorial_design&amp;diff=280&amp;oldid=prev</id>
		<title>Editor iHTS: Created page with &quot;A design that allows for evaluating the effects of multiple interventions and their interactions within a clinical trial.  &#039;&#039;&#039;Note:&#039;&#039;&#039; Most trials consider only one experimental intervention, comparing it with one or more options or a placebo. In a trial using a 2x2 factorial design, participants are allocated to one of four possible combinations.  For example, in a randomised controlled trial of a nicotine replacement therapy and counselling, participants would be alloc...&quot;</title>
		<link rel="alternate" type="text/html" href="http://glossary.i-hts.org/index.php?title=Factorial_design&amp;diff=280&amp;oldid=prev"/>
		<updated>2023-11-08T15:17:41Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;A design that allows for evaluating the effects of multiple interventions and their interactions within a clinical trial.  &amp;#039;&amp;#039;&amp;#039;Note:&amp;#039;&amp;#039;&amp;#039; Most trials consider only one experimental intervention, comparing it with one or more options or a placebo. In a trial using a 2x2 factorial design, participants are allocated to one of four possible combinations.  For example, in a randomised controlled trial of a nicotine replacement therapy and counselling, participants would be alloc...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;A design that allows for evaluating the effects of multiple interventions and their interactions within a clinical trial.&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Note:&amp;#039;&amp;#039;&amp;#039; Most trials consider only one experimental intervention, comparing it with one or more options or a placebo. In a trial using a 2x2 factorial design, participants are allocated to one of four possible combinations.  For example, in a randomised controlled trial of a nicotine replacement therapy and counselling, participants would be allocated to: nicotine replacement therapy alone, counselling alone, both, or neither. In this way it is possible to test the independent effect of each intervention on smoking cessation and the combined effect of (interaction between) the two interventions.&lt;br /&gt;
&lt;br /&gt;
[http://htaglossary.net/factorial-design]&lt;/div&gt;</summary>
		<author><name>Editor iHTS</name></author>
	</entry>
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